Position Type:

  • Lassonde Undergraduate Research Award‐ summer research
  • NSERC USRA

Position Title: Research Assistant/summer researcher

Location: BCEE 328

Professor: Hossein Kassiri

Department: Electrical Engineering and Computer Science

Contact for Professor (Email, phone): Email: Hossein@eecs.yorku.ca

# of positions available: 1

Project Description :

Over the past decade, brain electrical stimulation has been shown as an

alternative solution for patients with neurological disorders who are refractory to drugs

or brain surgery. However, electrical stimulation methods strongly suffers from lack of

spatial resolution and specificity. Moreover, electrical stimulation is often five-to-six

orders of magnitude larger than the field potential signals that could be used for

detecting brain activity. This feed-forward cross-contamination pathway makes closing

the electrical feedback loop challenging for both research and therapy systems.

Optogenetic stimulation is a relatively new technological advance that may

overcome the aforesaid limitations of electrical stimulation. The major benefit of

optogenetic stimulation is the unprecedented specificity it provides, allowing spatial,

temporal, and cell-type selective modulation of neuronal circuits. Equipped with such

tools, it is now possible to begin to address some of the fundamental unanswered

questions in neurological disorders such as epilepsy, to dissect epileptic neuronal

circuits, and to develop new intervention strategies. Such specificity of intervention also

has the potential for direct therapeutic benefits, allowing healthy tissue and network

functions to continue unaffected.

In Integrated Circuits and Systems Lab, we are developing a fully-implantable

wireless neuro-stimulator IC (integrated circuit) to be used with micro-scale LEDs for

optogenetic stimulation. While the IC is designed by a graduate student, a board-level

prototype must be developed in parallel to characterize the envisioned solution using

in-vitro experiments.

Duties and Responsibilities of the student:

The successful candidate will be responsible of developing a board-level ontogenetic

device using off-the-shelf electronic component and conducting its electrical and invitro

characterization.

Skills and Qualifications:

The student should have the following qualifications:

- Familiarity with electronic circuits and systems.

- PCB design experience is a plus.

- Self-driven and interested in the field of biomedical electronics

Degrees, courses and Disciplines prerequisite*:

- Minimum requirement: EECS 2200, 2210 or equivalent

- Preferred: EECS 3611 and EECS3201 or equivalent

Stipend TBD

Willing to host external students? Yes

Duration: 16 weeks minimum

Start Date: 05/01/2018 (estimated)

End Date: 08/31/2018 (estimated)

If you are interest in this research project, please contact Hossein Kassiri at Hossein@eecs.yorku.ca